Utilization of Repeat Patient Sample as an Internal Quality Control Measure: The Pilot Study Results
Abstract
Introduction: To provide reliable result for every sample, internal and external quality control (QC) measures) must be in place in a clinical laboratory. The present study was designed to asses and re-establishes the utility and efficacy of random patient samples as a regular QC practice.
Method: For quality control (QC) of hematology section a random repeated patient’s sample technique was practiced, the difference between present day sample result and that on immediate previous day was calculated. The differences for Hemoglobin, Red Blood Cells Total Leukocyte count and Platelet count were noted. The mean and standard deviation of difference were calculated, with and without considering the plus (+) and minus (-) sign. Levey–Jenning’s chart (LJ chart) and Cusum chart of the signed and unsigned differences were plotted for all these four hemogram parameters.
Results: In a total of 246 repeat sample differences, a higher number (49) of Westgard rules violations was observed in LJ. Chart of signed differences, whereas lower number (30) of violations of Westgard rules were observed on analysis of absolute differences. The difference in signed and absolute differences for RBC parameter was statistically significant (p=0.045). Similarly, 16 out-of-limit events were identified on analysis of Cusum chart of signed differences. Whereas only 12 out-of-limit events were identified on analysis of Cusum chart of absolute differences.
Conclusion: Present study show that a QC strategy of daily planned repeat sample testing can improve the out-of-control error detection ability simply by using signed difference of repeat sample result and applying usual Westgard rules.
How to cite this article:
Thakur SK, Sinha AK, Sharma SK, Jahan A, Gupta R, Singh S, Singh H. Utilization of Repeat Patient Sample as an Internal Quality Control Measure: The Pilot Study Results. Rec Adv Path Lab Med. 2020;6(3&4):17-22.
DOI: https://doi.org/10.24321/2454.8642.202007
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