Moringa oleifera (Shigru): A Miraculous Medicinal Plant with Many Therapeutic Benefits
Keywords:Shigru, Moringa, Folk Medicine, Analgesic, Anti-Inflammatory, Shoothhar, Sweedjanan
Two species of Moringa are recorded from India, of which one, M. Oleifera, is widely cultivated in the tropics for its edible fruits. M. Oleifera (Drumstick tree) is indigenous to the Himalayan foothills of South Asia from north-eastern Pakistan (33 °N, 73 °E) to northern West Bengal State in India and northeastern Bangladesh where it is commonly found from sea level to 1,400 m on recent alluvial land or near riverbeds and streams. It grows at elevations from sea level to 1400 m. Numerous medicinal uses of Moringa oleifera has, also recognized namely antihypertensive, diuretic and cholesterol lowering activities, antispasmodic, antiulcer and hepatoprotective activities, antibacterial and antifungal activities, antitumor and anticancer activities, aqueous leaf extracts regulate thyroid hormone and can be used to treat hyperthyroidism and exhibit an antioxidant effect. A recent report showed that M. oleifera leaf may be applicable as a prophylactic or therapeutic anti-HSV (Herpes simplex virus type 1) medicine and may be effective against the acyclovir-resistant variant. Moringa seeds have specific protein fractions for skin and hair care. Two new active components for the cosmetic industry have been extracted from oil cake. Purisoft® consists of peptides of the Moringa seed. It protects the human skin from environmental influences and combats premature skin aging. With dual activity, antipollution and conditioning/ strengthening of hair, the M. oleifera seed extract is a globally acceptable innovative solution for hair care. It works on multisystem and helps to alleviate the many diseases; hence it is termed as miraculous tree.
How to cite this article:
Rana M, Maurya BN, Byadgi PS et al. Moringa oleifera (Shigru): A Miraculous Medicinal Plant with Many Therapeutic Benefits. Int J Adv Res Med Chem 2021; 3(1): 1-7.
Fahey. Moringa oleifera, A Review of Medical evidence for its Nutritional, Theraputic and Prophylactic properties. 215-220.
Mughal MH, Ali G, Srivastava PS et al. Improvement of drumstick (Moringa pterygosperma Gaertn.) – a unique source of food and medicine through tissue culture. Hamdard Med 1999; 42: 37-42.
The Wealth of India (A Dictionary of Indian Raw Materials and Industrial Products). Raw Materials, Vol. VI: L-M; Council of Scientific and Industrial Research: New Delhi. 1962; 425-429.
Dahot MU. Vitamin contents of flowers and seeds of Moringa oleifera. Pak J Biochem 1988; 21: 1-24.
Faizi S, Siddiqui B, Saleem R et al. Isolation and structure elucidation of new nitrile and mustard oil glycosides from Moringa oleifera and their effect on blood pressure. J Nat Prod 1994a; 57: 1256-1261.
Faizi S, Siddiqui B, Saleem R et al. Novel hypotensive agents, niazimin A, niazimin B, niazicin A and niazicin B from Moringa oleifera; Isolation of first naturally occurring carbamates. J Chem Soc Perkin Trans 1994b; 1: 3035-3640.
Faizi S, Siddiqui BS, Saleem R et al. Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry 1995; 38: 957-963.
Gilani AH, Aftab K, Suria A et al. Pharmacological studies on hypotensive and spasmodic activities of pure compounds from Moringa oleifera. Phytother Res 1994a; 8: 87-91.
Faizi S, Siddiqui BS, Saleem R et al. Hypotensive constituents from the pods of Moringa oleifera. Planta Med 1998; 64: 225–228.
Caceres A, Saravia A, Rizzo S et al. Pharmacologic properties of Moringa oleifera: 2: Screening for antispasmodic, anti-inflammatory and diuretic activity. J Ethnopharmacol 1992; 36: 233–237.
Morton JF. The horseradish tree, Moringa pterigosperma (Moringaceae). A boon to arid lands. Econ Bot 1991; 45: 318–333.
Ghasi S, Nwobodo E, Ofili JO. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats. J Ethnopharmacol 2000; 69: 21–25.
Mehta LK, Balaraman R, Amin AH et al. Effect of fruits of Moringa oleifera on the lipid profile of normal and hypercholesterolaemic rabbits. J Ethnopharmacol 2003; 86: 191-195.
Gilani AH, Aftab K, Shaheen F et al. Antispasmodic activity of active principle from Moringa oleifera. In Natural Drugs and the Digestive Tract, Capasso F, Mascolo N (eds). EMSI: Rome 1992; 60-63.
Dangi SY, Jolly CI, Narayana S. Antihypertensive activity of the total alkaloids from the leaves of Moringa oleifera. Pharm Biol 2002; 40: 144-148.
Pal SK, Mukherjee PK, Saha BP. Studies on the antiulcer activity of Moringa oleifera leaf extract on gastric ulcer models in rats. Phytother Res 1995a; 9: 463-465.
Ruckmani K, Kavimani S, Anandan R et al. Effect of Moringa oleifera Lam on paracetamol-induced hepatoxicity. Indian J Pharm Sci 1998; 60: 33-35.
Gilani AH, Janbaz KH, Shah BH. Quercetin exhibits hepatoprotective activity in rats. Biochem Soc Trans 1997; 25: 85.
Rao VA, Devi PU, Kamath R. In vivo radioprotective effect of Moringa oleifera leaves. Indian J Exp Biol 2001; 39: 858–863.
Das BR, Kurup PA, Rao PL et al. Antibiotic principle from Moringa pterygosperma. VII. Antibacterial activity and chemical structure of compounds related to pterygospermin. Indian J Med Res 1957; 45: 191-196.
Eilert U, Wolters B, Nadrtedt A. The antibiotic principle of seeds of Moringa oleifera and Moringa stenopetala. Planta Med 1981; 42: 55-61.
Nikkon F, Saud ZA, Rehman MH et al. In vitro antimicrobial activity of the compound isolated from chloroform extract of Moringa oleifera Lam. Pak J Biol Sci 2003; 22: 1888-1890.
Bhatnagar SS, Santapau H, Desai JDH et al. Biological activity of Indian medicinal plants. Part 1. Antibacterial, antitubercular and antifungal action. Indian J Med Res 1961; 49: 799-805.
Caceres A, Cabrera O, Morales O et al. Pharmacological properties of Moringa oleifera. 1: Preliminary screening for antimicrobial activity. J Ethnopharmacol 1991; 33: 213-216.
Murakami A, Kitazono Y, Jiwajinda S et al. Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirement for inhibition of tumor-promoter-induced Epstein-Barr virus activation. Planta Med 1998; 64: 319-323.
Guevara AP, Vargas C, Sakurai H et al. An antitumor promoter from Moringa oleifera Lam. Mutat Res 1999; 440: 181-188.
Bharali R, Tabassum J, Azad MRH. Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolizing enzymes, anti-oxidant parameters and skin papillomagenesis in mice. Asia Pacific J Cancer Prev 2003; 4: 131-139.
Caceres A, Lopez S. Pharmacologic properties of Moringa oleifera: Effect of seed extracts in the treatment of experimental Pyodermia. Fitoterapia 1991; 62: 449-450.
Pal SK, Mukherjee PK, Saha K et al. Antimicrobial action of the leaf extract of Moringa oleifera Lam. Ancient Science of Life 1995b; 14: 197-199.
Tahiliani P, Kar A. Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats. Pharmacol Res 2000; 41: 319-323.
Lipipun V, Kurokawa M, Suttisri R et al. Efficacy of Thai medicinal plant extracts against herpes simplex virus type 1 infection in vitro and in vivo. Antiviral Res 2003; 60: 175–180.
Bhattacharya SB, Das AK, Banerji N. Chemical investigations on the gm exudates from Sonja (Moringa oleifera). Carbohydr Res 1982; 102: 253-262.
Makonnen E, Hunde A, Damecha G. 1997. Hypoglycaemic effect of Moringa stenopetala aqueous extract in rabbits. Phytother Res 11: 147–148.
Stussi IA, Freis O, Moser P, Pauly G. 2002. Laboratoires Sérobiologiques Pulnoy, France http://www. laboratoiressero biologiques.
Siddhuraju P, Becker K. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agro-climatic origins of drumstick tree (Moringa oleifera Lam.). J Agric Food Chem 2003; 15: 2144-2155.
Fuglie. Chemical investigations on the gm exudates from (Moringa oleifera). Phytother 2001; 10: 253-259.
Lalas S, Tsaknis J. Extraction and identification of natural antioxidants from the seeds of Moringa oleifera tree variety of Malavi. J Am Oil Chem Soc 2002; 79: 677-683.