Immunogenicity and Personalized Medicine: Shaping Tailored Therapies for Better Patient Outcomes
Keywords:
Immunogenicity, Personalized Medicine, Biologic Therapies, Monoclonal Antibodies, Gene Therapy, Genetic Profiling, Immunosuppression, Tailored Treatment, Pharmacogenomics, Patient OutcomesAbstract
Immunogenicity, the ability of a therapeutic agent to provoke an immune response, poses significant challenges in the field of medicine, particularly in the treatment of diseases using biologic agents such as monoclonal antibodies, vaccines, and gene therapies. As the field of personalized medicine advances, understanding the role of immunogenicity is crucial in optimizing treatment outcomes. Personalized medicine tailors therapies based on individual patient characteristics, including genetic, environmental, and lifestyle factors. This review explores how immunogenicity impacts the effectiveness and safety of biologic therapies and its integration into personalized medicine. By leveraging genetic profiling, biomarker discovery, and novel therapeutic designs, it is possible to reduce the risks of immune responses and enhance treatment efficacy. Through understanding the immunogenic profile of patients, healthcare providers can make informed decisions to offer more effective, individualized treatments, thus improving patient outcomes. This review also examines current strategies aimed at mitigating immunogenicity in biologic therapies, including the engineering of biologics, immunosuppressive protocols, and the role of pharmacogenomics in customizing treatments.
How to cite this article:
Kumar N, Prasad P. Immunogenicity and
Personalized Medicine: Shaping Tailored
Therapies for Better Patient Outcomes. Rec
Trends Pharm Tech IndI 2025 7(1): 43-48.
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