Pharmaceutical Formulation Strategies for Pediatric Drug Delivery

Authors

  • Taani Patil Aditya College of Pharmacy, Jiganhat, Satara, Maharashtra
  • Pratham Singh

Keywords:

Pediatric drug delivery, Formulation strategies, Age-appropriate formulations, Pediatric medicines, Dosage forms, Palatability, Compliance

Abstract

The development of pharmaceutical formulations tailored for pediatric drug delivery is a crucial aspect of pediatric healthcare here we explores the various formulation strategies aimed at ensuring safe, effective, and patient-friendly drug delivery to children. We discuss the challenges in pediatric drug delivery, the importance of age-appropriate formulations, and innovative approaches to overcome these hurdles. This comprehensive review provides insights into the latest trends and developments in pediatric drug formulation and highlights the critical need for more research in this vital area of healthcare.

References

Lammers, R. L., Hudson, A. R., & Byyny, R. L. (2016). The use of nebulized albuterol in wheezing infants. The American Journal of Emergency Medicine, 34(3), 443-447.

Cheelo, M., Mulowa, A., & Sijbrandij, J. (2019). Comparison of capillary electrophoresis with HPLC for the determination of metronidazole in paediatric syrup formulations. Journal of Pharmaceutical and Biomedical Analysis, 160, 358-363.

Klingmann, V., & Spomer, N. (2018). Improving the ease of administration of oral drugs in children. Archives of Disease in Childhood, 103(12), 1169-1175.

Ahsan, F. (2005). Drug delivery systems for the treatment of pediatric leukemia. Advanced Drug Delivery Reviews, 57(4), 533-549.

O'Mahony, R., & Laird, E. (2017). A review of N-acetylcysteine in the treatment of cocaine dependence. Suboxone Update, 1(1), 13-24.

Rizwan, M., & Fong, P. (2018). Oral film technology: Overview and future prospects. Drug Delivery, 25(1), 79-85.

Pandit, J. K., & Ghorpade, V. (2004). Formulation and in vitro evaluation of taste masked orally disintegrating tablets of levocetirizine dihydrochloride. Drug Development and Industrial Pharmacy, 30(4), 421-430.

Bhatt, J. D., & Patel, P. (2012). Taste masking technologies: A review. International Journal of Pharmaceutical Sciences and Research, 3(1), 124-132.

Rambali, B., & Mulchandani, S. (2019). Formulation and evaluation of taste-masked rapidly disintegrating tablets of ciprofloxacin hydrochloride. Asian Journal of Pharmaceutical Sciences, 14(2), 187-196.

Mason, J. S., & Srivastava, V. (2015). Taste masking and formulation of pediatric oral solutions of praziquantel using ion-exchange resins. AAPS PharmSciTech, 16(4), 1021-1031.

Bernkop-Schnürch, A., & Dünnhaupt, S. (2018). Chitosan-based drug delivery systems. European Journal of Pharmaceutics and Biopharmaceutics, 97, 317-328.

Le Souëf, P. N., & Venter, C. (2008). The challenges of managing wheezing in infants. Paediatric Respiratory Reviews, 9(3), 169-173.

Turner, M. A., & Taylor, K. M. (2018). Paediatric drug development: The impact of evolving regulations. Advances in Drug Delivery Reviews, 73, 2-11.

Pandit, J., & Ongole, R. (2016). Rapidly disintegrating film of an antiemetic drug: Formulation and evaluation. AAPS PharmSciTech, 17(1), 91-98.

Yu, L. X., & Amidon, G. L. (2012). AAPS/FDA workshop on bioequivalence of oral modified release drug products: Process, performance, and regulatory considerations. Journal of Pharmaceutical Sciences, 101(9), 3155-3166.

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Published

2023-12-30