Manufacturing process with Chemical Reactions and mass Balance for 6 Pharmaceutical Drugs

Authors

  • Dr. Ashok K Rathoure Eco Group of Companies
  • Savita Goyal Aggarwal GRD IMT, 214, Rajpur Road, Dehradun UK - 248001, India.

Keywords:

Aceclofenac, Bifonazole, Clotrimazole, Drugs, Diclofenac Sodium, Pyridoxine Acetonide Hydrochloride

Abstract

Diclofenac is a non-steroidal anti-inflammatory drug. Bifonazole is a substituted imidazole antifungal
agent structurally related to other drugs in this group. It possesses a broad spectrum of activity in vitro
against dermatophytes, moulds, yeasts, dimorphic fungi and some Gram-positive bacteria. Aceclofenac is
used to relieve pain in the conditions like osteoarthritis, rheumatoid Arthritis and ankylosing spondylitis.
Clotrimazole is used to treat yeast infections of the vagina, mouth and skin such as athlete’s foot, jock
itch and body ringworm. It can also be used to prevent oral thrush in certain patients. Dihydralazine
sulfate is a vasodilator and an antihypertensive agent. It relaxes arterial smooth muscle by inhibiting the
accumulation of intracellular free calcium. By relaxing vascular smooth muscle, vasodilators act to decrease
peripheral resistance. Pyridoxine hydrochloride is the 4-methanol form of Vitamin B6 which is converted
to Pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin,
norepinephrine), sphingolipids, aminolevulinic acid. Here, we have presented the manufacturing process
along with mass balance for 6 pharmaceutical drugs.

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Published

2018-10-26

How to Cite

Rathoure, D. A. K., & Aggarwal, S. G. (2018). Manufacturing process with Chemical Reactions and mass Balance for 6 Pharmaceutical Drugs. Journal of Drug Discovery and Development ( ISSN:2581-6861), 1(1), 54-64. Retrieved from http://www.medicaljournalshouse.com/index.php/JDrug-Discovery-Development/article/view/55

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Vol. 1 No. 1 (2017): Journal of Drug Discovery and Development

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