http://www.medicaljournalshouse.com/index.php/Int-J-Microbiology-Immunology/issue/feed 2025-04-24T11:06:51+00:00 . admin@adrpublications.in Open Journal Systems International Journal of Advanced Research in Microbiology and Immunology is devoted to the publication of original scientific research findings, methodological developments, and opinions in the form of original and review articles, brief reports, short articles, letters to the editor, proceedings of symposia, debates, etc. The Journal focuses on research and reviews on Microbiology, Immunology, Bacteriology, Mycology, Protozoology, Phycology, Parasitology, Nematology, Microbial cytology, Microbial physiology, Microbial ecology, Microbial genetics, Cellular microbiology, Evolutionary microbiology, Microbial taxonomy, Microbial systematics, Generation microbiology, Classical immunology, Clinical immunology, Computational immunology, Diagnostic immunology, Evolutionary immunology, Systems immunology, Immunomics, Immunoproteomics, Immunophysics, Immunochemistry, Ecoimmunology, Immunopathology, Nutritional immunology, Psychoneuroimmunology, Reproductive immunology, Circadian immunology, Immunotoxicology, Palaeoimmunology, Tissue-based immunology, Systems microbiology, Molecular microbiology, Nano microbiology, Exo microbiology, Medical microbiology, Industrial microbiology, Microbial ecology, Microbial diversity, Bioremediation, Agricultural microbiology, Microbial Phylogenetics, Environmental microbiology, Annals of Clinical Microbiology and Antimicrobials, Antimicrobial Agents and Chemotherapy, Antiviral Research, Infection, Genetics and Evolution, Intervirology, Microscopy and Microanalysis, Virology, Viral therapy. Thank you forshowing interest in Int. J. of Microbiology and Immunology. http://www.medicaljournalshouse.com/index.php/Int-J-Microbiology-Immunology/article/view/1403 2024-12-27T21:25:36+00:00 Noureddine Bribi noureddine.bribi@univ-bejaia.dz Mohamed Sofiane Merakeb mohamedsofiane.merakeb@univ-bejaia.dz Safia Afenai safia.affenai@univ-bejaia.dz

<p>Background: Fumaria capreolata has been used in North African traditional medicine for its gastrointestinal benefits and anti-inflammatory effects.<br />Objective: This study explores the intestinal anti-inflammatory effects of total alkaloids extracted from the aerial parts of Fumaria capreolata (AFC) against acetic acid-induced experimental colitis in mice.<br />Methods: Intestinal anti-inflammatory effects of AFC (6.25, 12.5, and 25 mg/kg) were evaluated using the acetic acid-induced ulcerative colitis model in male NMRI mice. Colonic damage was assessed through colitis parameters and histological analysis of the colon.<br />Results: This study demonstrated that pre-treatment with AFC alleviates intestinal damage and clinical symptoms of ulcerative colitis. Histological analysis revealed that AFC helped preserve the integrity of the intestinal barrier. This finding was further supported by the colonic weight/length (W/L) ratio calculations.<br />Conclusion: AFC demonstrates potential as a promising candidate for preventing inflammatory diseases, such as colitis.</p> <p>How to cite this article:<br />Bribi N, Merakeb M S, Afenai S. Effect of Fumaria<br />Capreolata Total Alkaloid Extract on Acetic Acid-<br />induced Ulcerative Colitis in NMRI Mice. Int J Adv<br />Res MicroBiol Immunol. 2025;8(1):1-6.</p>

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