Endometrial Polyp and Its Clinico-Pathological Correlation
Abstract
Background: Endometrial polyps are localized overgrowths of the endometrial tissue, commonly seen in women presenting with abnormal uterine bleeding (AUB). Though generally benign, they may coexist with or mimic precancerous or malignant lesions, necessitating a clinico- pathological evaluation. Objective: To evaluate the clinical presentation and histopathological features of endometrial polyps, and to correlate these findings with non-polypoidal endometrial lesions to determine distinguishing features that can aid diagnosis and reduce unnecessary hospital admissions. Methods: A retrospective study was conducted on 38 cases over two years (2022–2024) in the Department of Pathology, Amrita Institute of Medical Sciences, Faridabad. Histopathological data and clinical profiles were collected for each case. Statistical analysis was conducted using parametric tests and ANOVA. All endometrial biopsies and hysterectomy specimens were included; malignancies and non-endometrial polyps were excluded. Results: Out of 38 cases, 4 (10.53%) were endometrial polyps and 34 (89.47%) were non-polypoidal lesions. The mean age of patients with polyps was 43.25 years, while for non-polyp cases it was 45.24 years, with no significant age-related difference. Polypoidal lesions presented primarily with AUB (75%) and proliferative endometrium (100%), with one showing simple hyperplasia without atypia. Non- polypoidal lesions exhibited a broader range of endometrial phases, including proliferative (73.53%) and secretory (26.47%) types, without any hyperplasia or malignancy. Conclusion: Endometrial polyps are most commonly seen in perimenopausal women with AUB and display distinct histological patterns, particularly proliferative changes. However, clinically and demographically, they are indistinguishable from non-polypoidal lesions. Accurate pathological diagnosis remains essential for guiding patient management, avoiding overtreatment, and reducing the financial burden on patients. How to cite this article:Gosai A, Vibbha I, Gandhi A. Endometrial Polyp
and Its Clinico-Pathological Correlation. Rec Adv
Path Lab Med. 2024;10(3&4):16-20. DOI: https://doi.org/10.24321/2454.8642.202408
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