International Journal of Advanced Research in Medicinal Chemistry

Enzymatic and Microbial Transformations of Natural Compounds: Expanding Horizons in Green Synthesis

Saniya Pandey, Tripti Kumar — Sat, 30 Dec 2023 00:00:00 +0000

Enzymatic and microbial transformations of natural compounds have emerged as powerful tools in the realm of green synthesis, offering sustainable and efficient alternatives to traditional chemical methods. In this review we explores the recent advancements in this field, highlighting the diverse applications and potential of enzymes and microorganisms in the synthesis of valuable compounds. The integration of biocatalysis and microbial processes not only provides environmentally friendly routes but also expands the scope of accessible chemical space, paving the way for innovative applications in pharmaceuticals, food, and fine chemicals.

Bioinformatics Approaches in Natural Product Research Unraveling Nature's Chemical Diversity

Lovepreet Singh, Harmandeep kaur — Sat, 30 Dec 2023 00:00:00 +0000

Natural products derived from plants, microbes, and marine organisms have been a rich source of bioactive compounds with diverse pharmaceutical applications. The exploration of this vast reservoir of chemical diversity has been greatly enhanced by the integration of bioinformatics approaches into natural product research. This review article provides an overview of the key bioinformatics tools and methodologies employed in deciphering, analyzing, and exploiting natural products for various therapeutic purposes.

How to cite this article:
Kaur H, Singh L. Bioinformatics Approaches in Natural Product Research: Unraveling Nature’s Chemical Diversity. Int J Adv Res Med Chem 2023; 5(2): 1-5

CRISPR Technology in Drug Discovery: Revolutionizing Target Identification and Therapeutic Development

Prakash Reddy — Sat, 30 Dec 2023 00:00:00 +0000

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology has emerged as a revolutionary tool in the field of drug discovery, providing researchers with unprecedented precision and efficiency in gene editing. In this article we explore the applications of CRISPR technology in drug discovery, with a focus on target identification and therapeutic development. We delve into the underlying mechanisms of CRISPR, its evolution, and the diverse CRISPR-based methodologies employed in drug discovery pipelines. The paper also addresses the challenges and ethical considerations associated with CRISPR applications in the pharmaceutical industry.

How to cite this article:
Reddy P. CRISPR Technology in Drug Discovery: Revolutionizing Target Identification and Therapeutic Development. Int J Adv Res Med Chem 2023; 5(2): 6-9

Monoclonal Antibodies in Therapeutics: A Revolution in Precision Medicine

Aporva Tyagi, Nikki kumari — Sat, 30 Dec 2023 00:00:00 +0000

Monoclonal antibodies (mAbs) have emerged as a groundbreaking class of therapeutic agents, revolutionizing the landscape of medicine and significantly impacting the treatment of various diseases. It explores the development, mechanisms of action, and therapeutic applications of monoclonal antibodies, highlighting their immense potential in precision medicine.

How to cite this article:
Tyagi A, Kumari N. Monoclonal Antibodies in
Therapeutics: A Revolution in Precision Medicine.
Int J Adv Res Med Chem 2023; 5(2): 18-22

Structural Modifications of Natural Products for Enhanced Bioactivity: A Review

Kiran Palliwal, Shruti Singh — Sat, 30 Dec 2023 00:00:00 +0000

Natural products have long been a rich source of bioactive compounds with diverse therapeutic properties. However, the structural complexity and limited bioavailability of many natural products have spurred significant research efforts towards modifying their structures to enhance bioactivity.

How to cite this article:
Palliwal K, Singh S. Structural Modifications of
Natural Products for Enhanced Bioactivity: A
Review. Int J Adv Res Med Chem 2023; 5(2): 23-28